Freshteh Toghrol, Ph.D.
Founder and Director of the Microarray Research Laboratory
U.S. EPA, Office of Pesticide Programs
Biological & Economic Analysis Division (7503C)
Microarray Research Laboratory
701 Mapes Road, Fort Meade, MD 20755
E-mail: Toghrol.freshteh@epa.gov
Phone: (410) 305-2755
Fax: (410) 305-3091
EDUCATION
Doctor of Philosophy in Biochemistry, University of Southampton, Southampton, England
PROFESSIONAL EXPERIENCE
2002 to present Senior Science Advisor, Director. Microarray Research Laboratory
United States Environmental Protection Agency, Fort Meade, Maryland
1994 to 2002 Chemist. Office of Pesticide Programs / Biopesticides and Pollution Prevention
United States Environmental Protection Agency, Arlington, Virginia
1988 to 1994 Chemist. Office of Pesticide Programs / Health Effect Division
United States Environmental Protection Agency, Arlington, Virginia
1987 to 1988 Researcher. National Institutes of Child Development
National Institutes of Health, Bethesda, Maryland
Textbooks
An Introduction to Biochemistry, Tehran University Press, 1973, Second Edition, 1977 (600 pages translated/edited).
Peer-reviewed Articles
Small, D.A., Chang, W., Toghrol, F., and Bentley, W.E. Comparative global transcription analysis of sodium hypochlorite, peracetic acid, and hydrogen peroxide on Pseudomonas aeruginosa. Submitted.
Small, D.A., Chang, W., Toghrol, F., and Bentley, W.E. Toxicogenomic Effects of Sodium Hypochlorite on Pseudomonas aeruginosa. Submitted.
Chang, W., Toghrol, F., and Bentley, W.E. Toxicogenomic response of Staphylococcus aureus to peracetic acid. Environ. Sci. Technol. 2006, In press.
Chang, W., Small, D.A., Toghrol, F., and Bentley, W.E Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide. J. Bacteriol. 2006, 188(4), 1648-1659.
Chang, W., Small, D.A., Toghrol, F., and Bentley, W.E. Microarray analysis of Pseudomonas aeruginosa reveals induction of pyocin genes in response to hydrogen peroxide. BMC Genomics 2005, 6(1):115.
Chang, W., Small, D.A., Toghrol, F., and Bentley, W.E. Toxicogenomic Effects of Peracetic Acid on Pseudomonas aeruginosa PA01, Environ. Sci. Technol. 2005, 39(15):5893-5899.
*Toghrol, P., Kimura, T., and Owens, I.S., Expression of UDP-Glucuronosyltransferase cDNA in Saccharomyces Cerevisiae as a Membrane-Bound and as a Cytosolic Form. Biochemistry 1990, 29(9):2349-2356.
Toghrol, F., Southerland, W.M. Thiobacillus novellus Sulfite Oxidase: Subunit Structure and Enzymic Cofactors. Fed. Pro. (abstract) 1983, 42:811.
*Southerland, W.M., Toghrol, F., Sulfite Oxidase Activity in Thiobacillus novellus. J. Bacteriol. 1983, 56:941-944.
*Toghrol, F., Southerland, W.M., Purification of Sulfite Oxidase from Thiobacillus novellus: Evidence for Presence of Heme and Molybdenum. J. Bio. Chem. 1983, 256:6762-6766.
Southerland, W.M., Akogyeram, C.O., Toghrol, F., Scherrer, R. Interaction of Bisulfite with Unsaturated Fatty Acids. J. Toxicology and Environmental Health 1982, 479-491.
Toghrol, F., Johnson, R. Southerland, W.M. Comparison of Thiobacillus novellus and Mammalian Sulfite Oxidase. Fed. Pro. (abstract) 1981, 40:1489.
*Toghrol, F., Franklin, R.B., Costello, L.C. Citrate Synthesis from Fatty Acids and Amino Acids in Rat Ventral Prostate. Enzyme 1980, 25:371-376.
*articles and the unpublished work in the thesis have been cited in numerous book reviews and in well established journals, i.e. book reviews as follows:
Advances in Comparative Physiology and Biochemistry 1968.
Crustacean Metabolism, A.K. Huggins and K.A. Munday 1968, 3:271-353.
Chemical Zoology K.A. Munday and Poat P.C. 1971, 191-211.
Electron Spin Resonance-A Specialist Periodical Report, 1985.
Metalloproteins Blackburn-V.J. 1985, 9:291-323.
Scientific Journals such as Comp. Biochem, Biophysics, Biochem. J., Int. J. Biochem., Journal of Steroid Biochemistry, Biochemistry, Biochemical journal, Archives of Microbiology and J. Biological Chem.